3 credits
Spring 2025 Lecture Upper Division
This course exposes students to the basic principles of immunology, teaches students to use those principles to understand the cause of immunological disease and the basis of immunoprophylaxis and immunotherapy, and provides students with sufficient information to understand the principles and challenges of gene therapy and the application of genomics to future drug development.
Learning Outcomes1The basic components of the immune system and their roles in innate and adaptive immunity.
2The development and function of lymphocytes in adaptive immunity.
3The molecular basis of antibody diversity.
4How antigens are recognized by T cells.
5How B cells develop and function in the body.
6How T cells develop in the body and differentiate into specialized subsets.
7How lymphocytes undergo positive and negative selection.
8How B cells and T cells are activated and participate in adaptive immunity.
9The basis of MHC polymorphism and the role on the immune response.
10How the complement system is activated and plays its role in immune responses.
11How the cellular components of the innate and adaptive immune systems combine to generate an effective response against pathogens.
12How the body remembers a previous infection.
13The types and causes of immunodeficiency diseases.
14How infection with HIV affects the immune system.
15How the immune system sometimes recognizes harmless antigens (allergic reactions).
16How the immune system can damage healthy tissue.
17The basis and practice of immunization.
18How the immune system complicates organ transplantation.
19How the immune system recognizes cancer cells and can be used to combat cancer.
Prerequisites
Restrictions
made by Purdue students.