1Recognize and describe diseased tissue grossly and microscopically, explain the sequence of events in the development and outcome of observed lesions, explain the interplay among different organs or tissues, and predict the effect of the response to injury on the host.

2Correlate clinical and pathologic findings. Predict the organ/tissue site and nature of expected lesions when given the clinical presentation. Predict clinical signs when given the gross or microscopic lesions.

3Correlate gross lesions (or lack thereof!) with histologic, cytologic, and molecular changes.

4Categorize lesions as degeneration or necrosis, inflammation, circulatory disturbance, or disturbance of growth. Recognize that a given lesion may (and often does) fall into more than one category.

5Formulate a logical and practical differential diagnosis based on the host signalment, the affected organ or tissue, the lesion categorization, and environmental influences (risk factors, seasonal or geographical influences, etc.).