1Apply an advanced understanding and knowledge of biochemistry to pharmaceutical sciences and the practice of pharmacy.

2Demonstrate advanced understanding of biochemistry including integration of multiple areas of metabolism in the causation of disease and in physiologic homeostasis; biochemical signal transduction paradigms and concepts; the basis of complex biotechnology methods for disease diagnosis and disease research (recombinant DNA, proteomics, genomics, metabolomics), and the development of experimental therapeutics (gene transfer, reverse genetics, siRNA); and the advanced aspects of molecular transport, membrane function, enzyme kinetics, and the enzymology of drug metabolism.

3Understand the molecular basis of many idiopathic and acquired metabolic disease, of inborn disorders of metabolism, of diseases of aberrant molecular signaling, and of diseased of aberrant molecular transport; including the mechanisms of DNA damage and repair and the mechanisms of action of antimetabolites and of synthetic therapies for metabolic disorders.

4Demonstrate proficient knowledge of each of the content areas presented as well as demonstrate understanding of the each content area is sufficient for accurate application of those concepts to novel situations.